135 ASSOCIATION OF TRICUSPID REGURGITATION WITH OUTCOME IN ACUTE HEART FAILURE

Abstract Background Tricuspid regurgitation (TR) is common in chronic heart failure (HF) and associated with negative prognosis. However, evidence on prognostic implications of TR acute HF (AHF) lacking. Objectives We sought to investigate the association between mortality interaction pulmonary hypertension (PH) patients admitted for AHF. Methods enrolled 1176 consecutive a primary diagnosis AHF available non-invasive estimation arterial systolic pressure (PASP). Results Moderate-severe was present 352 (29.9%) older age more comorbidities. The prevalence PH (i.e., PASP>40mmHg), right ventricular dysfunction (RVD) mitral (MR) higher moderate-severe TR. At 1 year, 184 (15.6%) died. 1-year risk after adjustment other echocardiographic parameters (PASP, left ventricle ejection fraction – LVEF, RVD MR; HR=1.623, p=0.004) outcome maintained when clinical variables were added multivariable model (HR=1.515, p=0.035). consistent vs without PH, RVD, LVEF<50%. Patients coexistent had 3-fold compared no or (HR=2.920, p<0.001). Conclusions In hospitalized AHF, severity survival, regardless presence PH. combination conferred further incremental risk.